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Publications
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| 2010 |
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Understanding amyloid aggregation by statistical analysis of atomic force microscopy images
Jozef Adamcik, Jin-Mi Jung, Jérôme Flakowski, Paolo De Los Rios, Giovanni Dietler & Raffaele Mezzenga
Nature Nanotechnology |
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Microcontroller-driven fluid-injection system for atomic force microscopy
Kasas, S. ; Alonso, L. ; Jacquet, P. ; Adamcik, J. et al. In: Review of Scientific Instruments, vol. 81, num. 1, 2010, p. 013704
American Institute of Physics, 2010.
ISSN: 0034-6748
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Near-field scanning optical microscopy using polymethylmethacrylate optical fiber probes
Chibani, H. ; Dukenbayev, K. ; Mensi, M. ; Sekatskii, S. K. et al. In: Ultramicroscopy, vol. 110, num. 3, 2010, p. 211-215
Elsevier, 2010.
ISSN: 0304-3991
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Scanning Near-field Optical Microscopy-based Study of Local Dynamics of Receptor-Ligand Interactions at the Single Molecule Level
Mensi, Mounir ; Dukenbayev, Kanat ; Sekatski, Serguei ; Dietler, Giovanni In: Laser Physics, vol. 20, num. 1, 2010, p. 78-84
Date: 2010 |
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| 2009 |
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Persistence length and scaling properties of single-stranded DNA adsorbed on modified graphite
Rechendorff, K ; Witz, G; Adamcik, J ; Dietler, G
JOURNAL OF CHEMICAL PHYSICS, 131 (9): Art. No. 095103 SEP 7 2009
Abstract: We have characterized the polymer physics of single-stranded DNA (ssDNA) using atomic force microscopy. The persistence length l(p) of circular ssDNA adsorbed on a modified graphite surface was determined independently of secondary structure. At a very low ionic strength we obtained l(p)=9.1 nm from the bond correlation function. Increasing the salt concentration lead to a decrease in l(p); at 1 mM NaCl we found l(p)=6.7 nm, while at 10 mM NaCl a value l(p)=4.6 nm was obtained. The persistence length was also extracted from the root-mean-square end-to-end distance and the end-to-end distance distribution function. Finally, we have investigated the scaling behavior using the two latter quantities, and found that on long length scales ssDNA behaves as a two-dimensional self-avoiding walk.
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Stiffness Tomography by Atomic Force Microscopy
Roduit, C ; Sekatski, S ; Dietler, G ; Catsicas, S ; Lafont, F ; Kasas, S
BIOPHYSICAL JOURNAL, 97 (2): 674-677 JUL 22 2009
Abstract: The atomic force microscope is a convenient tool to probe living samples at the nanometric scale. Among its numerous capabilities, the instrument can be operated as a namo-indenter to gather information about the mechanical properties of the sample. In this operating mode, the deformation of the cantilever is displayed as a function of the indentation depth of the tip into the sample. Fitting this curve with different theoretical models permits us to estimate the Young's modulus of the sample at the indentation spot. We describe what to our knowledge is a new technique to process these curves to distinguish structures of different stiffness buried into the bulk of the sample. The working principle of this new imaging technique has been verified by finite element models and successfully applied to living cells.
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Complex studies of interactions between flaviviruses and laminin binding protein
Bogachek, ; Protopopova, E ; Loktev, V ; Zaitsev, B ; Favre, M ; Sekatskii, S ; Dietler, G
34th Congress of the Federation-of-European-Biochemical-Societies, Prague CZECH REPUBLIC
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Intracellular nanomanipulation by a photonic-force microscope with real-time acquisition of a 3D stiffness matrix
Bertseva, E ; Singh, ASG ; Lekki, J ; Thevenaz, P ; Lekka, M ; Jeney, S ; Gremaud, G ; Puttini, S ; Nowak, W ; Dietler, G ; Forro, L ; Unser, M ; Kulik, AJ
NANOTECHNOLOGY, 20 (28): Art. No. 285709 JUL 15 2009
Abstract: A traditional photonic-force microscope (PFM) results in huge sets of data, which requires tedious numerical analysis. In this paper, we propose instead an analog signal processor to attain real-time capabilities while retaining the richness of the traditional PFM data. Our system is devoted to intracellular measurements and is fully interactive through the use of a haptic joystick. Using our specialized analog hardware along with a dedicated algorithm, we can extract the full 3D stiffness matrix of the optical trap in real time, including the off-diagonal cross-terms. Our system is also capable of simultaneously recording data for subsequent offline analysis. This allows us to check that a good correlation exists between the classical analysis of stiffness and our real-time measurements. We monitor the PFM beads using an optical microscope. The force-feedback mechanism of the haptic joystick helps us in interactively guiding the bead inside living cells and collecting information from its ( possibly anisotropic) environment. The instantaneous stiffness measurements are also displayed in real time on a graphical user interface. The whole system has been built and is operational; here we present early results that confirm the consistency of the real-time measurements with offline computations
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Registration of long-range surface plasmon resonance by angle-scanning feedback and its implementation for optical hydrogen sensing
Konopsky, VN ; Basmanov, DV ; Alieva, EV ; Dolgy, DI ; Olshansky, ED ; Sekatskii, S ; Dietler, G
NEW JOURNAL OF PHYSICS Volume: 11 Article Number: 063049 Published: JUN 30 2009
Abstract: An optical technique devised for the detection of the ultrasharp angular resonance of long-range surface plasmons (LRSPs) is described. The LRSPs propagate along an 8 nm-thick palladium (Pd) film deposited on a one-dimensional photonic crystal structure and bordering a gas environment at another Pd film interface. At such a small metal film thickness, the scattering attenuation losses prevail over dissipation losses inside the film and we use this scattering as an input signal to pick up the angle of the surface plasmon resonance by a closed feedback loop via an angle-scanning piezomirror. As an implementation of this technique, we detected a 0.5% hydrogen concentration in nitrogen at room temperature with a signal/noise ratio of approximately 100 and response and recovery times of about 5 and 15 s, respectively.
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Temperature-Controled assembly of highly ordered/disordered dodecylamine layers on HOPG: Consequences for DNA patterning
Jozef Adamcik, Susana Tobenas, Giovanni di Santo, Dmitri Klinov, Giovanni Dietler
LANGMUIR 25 issue 5, 3159-3162 (2009)
Abstract: A traditional photonic-force microscope (PFM) results in huge sets of data, which requires tedious numerical analysis. In this paper, we propose instead an analog signal processor to attain real-time capabilities while retaining the richness of the traditional PFM data. Our system is devoted to intracellular measurements and is fully interactive through the use of a haptic joystick. Using our specialized analog hardware along with a dedicated algorithm, we can extract the full 3D stiffness matrix of the optical trap in real time, including the off-diagonal cross-terms. Our system is also capable of simultaneously recording data for subsequent offline analysis. This allows us to check that a good correlation exists between the classical analysis of stiffness and our real-time measurements. We monitor the PFM beads using an optical microscope. The force-feedback mechanism of the haptic joystick helps us in interactively guiding the bead inside living cells and collecting information from its ( possibly anisotropic) environment. The instantaneous stiffness measurements are also displayed in real time on a graphical user interface. The whole system has been built and is operational; here we present early results that confirm the consistency of the real-time measurements with offline computations |
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| 2008 |
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Imaging and Force Spectroscopy on DNA: Amplitude and Frequency Modulation on Single DNA Molecules
Giovanni Di Santo, Susana Tobenas, Jozef Adamcik, and Giovanni Dietler
G.I.T. Imaging & Microscopy 3/2008 |
Single-molecule avidin-biotin association reaction studied by force-clamp spectroscopy
Favre, M; Sekatskii, SK; Dietler, G
ULTRAMICROSCOPY 108 , 1135-1139 (2008) |
Conformation of circular DNA in two dimensions
Witz, G; Rechendorff, K; Adamcik, J; Dietler, G
PHYSICAL REVIEW LETTERS 101 , (2008) |
Single-molecule force spectroscopy of a protein globule covalently bound to a calcite surface
Denisov, NN; Shcheglova, LA; Sekatskii, SK; Dietler, G; Nadtochenko, VA
RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY B 2 , 350-353 (2008) |
The promotion of secondary structures in single-stranded DNA by drugs that bind to duplex DNA: an atomic force microscopy study
Adamcik, J; Valle, F; Witz, G; Rechendorff, K; Dietler, G
NANOTECHNOLOGY 19 , (2008) |
Probing nanomechanical properties from biomolecules to living cells
Kasas, S; Dietler, G
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 456 , 13-27 (2008) |
Single molecule fluorescence resonance energy transfer scanning near-field optical microscopy
Sekatskii, SK; Dietler, G; Letokhov, VS
CHEMICAL PHYSICS LETTERS 452 , 220-224 (2008) |
Immunochernical and single molecule force spectroscopy studies of specific interaction between the laminin binding protein and the West Nile virus surface glycoprotein E domain II
Bogachek, MV; Protopopova, EV; Loktev, VB; Zaitsev, BN; Favre, M; Sekatskii, SK; Dietler, G
JOURNAL OF MOLECULAR RECOGNITION 21 , 55-62 (2008) |
Scanning near-field optical microscope based on a double resonant fibre probe montage and equipped with time-gated photon detection
Serebryakov, DV; Sekatskii, SK; Cherkun, AP; Dukenbayev, K; Morozov, IV; Letokhov, VS; Dietler, G
JOURNAL OF MICROSCOPY-OXFORD 229 , 287-292 (2008) |
Force spectroscopy of the fibrin(ogen) - Fibrinogen interaction
Chtcheglova, LA; Haeberli, A; Dietler, G
BIOPOLYMERS 89 , 292-301 (2008) |
Elastic membrane heterogeneity of living cells revealed by stiff nanoscale membrane domains
Roduit, C; van der Goot, FG; Los Rios, P; Yersin, A; Steiner, P; Dietler, G; Catsicas, S; Lafont, F; Kasas, S
BIOPHYSICAL JOURNAL 94 , 1521-1532 (2008) |
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| 2007 |
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Scanning near-field optical microscope based on double-resonant fiber probe montage and its operation in liquids - art. no. 67282D
Dukenbayev, K; Sekatskii, SK; Serebryakov, DV; Zayats, AV; Dietler, G
ICONO 2007: NOVEL PHOTONICS MATERIALS; OPTICS AND OPTICAL DIAGNOSTICS OF NANOSTRUCTURES
672, D7282-D7282 (2007) |
Force-clamp spectroscopy with a small dithering of AFM tip, and its application to explore the energy landscape of single avidin-biotin complex
Favre, M; Chtcheglova, LA; Lapshin, DA; Sekatskii, SK; Valle, F; Dietler, G
ULTRAMICROSCOPY 107 , 882-886 (2007) |
Integration host factor alters LacI-induced DNA looping
Zurla, C; Samuely, T; Bertoni, G; Valle, F; Dietler, G; Finzi, L; Dunlap, DD
BIOPHYSICAL CHEMISTRY 128 , 245-252 (2007) |
Using biharmonic laser pumping for preparation of pure and entangled multiexciton states in clusters of resonantly interacting fluorescent centres
Basieva, IT; Basiev, TT; Dietler, G; Pukhov, KK; Sekatskii, SK
JOURNAL OF LUMINESCENCE 127 , 48-54 (2007) |
Elastic properties of the cell surface and trafficking of single AMPA receptors in living hippocampal neurons
Yersin, A; Hirling, H; Kasas, S; Roduit, C; Kulangara, K; Dietler, G; Lafont, F; Catsicas, S; Steiner, P
BIOPHYSICAL JOURNAL 92 , 4482-4489 (2007) |
Characterization of MAP1B heavy chain interaction with actin
Cueille, N; Blanc, CT; Popa-Nita, S; Kasas, S; Catsicas, S; Dietler, G; Riederer, BM
BRAIN RESEARCH BULLETIN 71 , 610-618 (2007) |
Fractal dimension and localization of DNA knots
Ercolini, E; Valle, F; Adamcik, J; Witz, G; Metzler, R; De Los Rios, P; Roca, J; Dietler, G
PHYSICAL REVIEW LETTERS 98 , (2007) |
Techniques for measuring microtubule stiffness
Kasas, S; Dietler, G
CURRENT NANOSCIENCE 3 , 85-96 (2007) |
Subwavelength-size local fluorescent sources based on color centers in LiF for scanning near-field optical microscopy
Sekatskii, SK; Dietler, G; Bonfigli, F; Loreti, S; Marolo, T; Montereali, RM
JOURNAL OF LUMINESCENCE 122 , 362-364 (2007) |
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| 2006 |
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Quantum control of exciton states in clusters of resonantly interacting fluorescent particles using biharmonic laser pumping
Basieva, IT; Basiev, TT; Dietler, G; Pukhov, KK; Sekatskii, SK
PHYSICAL REVIEW B 74 , (2006) |
Observation of single-stranded DNA on mica and highly oriented pyrolytic graphite by atomic force microscopy
Adamcik, J; Klinov, DV; Witz, G; Sekatskii, SK; Dietler, G
FEBS LETTERS 580 , 5671-5675 (2006) |
Kinetics of the interaction of desAABB-fibrin monomer with immobilized fibrinogen
Chtcheglova, LA; Vogel, M; Gruber, HJ; Dietler, G; Haeberli, A
BIOPOLYMERS 83 , 69-82 (2006) |
Simulations of electrophoretic collisions of DNA knots with gel obstacles
Weber, C; Rios, PDL; Dietler, G; Stasiak, A
JOURNAL OF PHYSICS-CONDENSED MATTER 18 , S161-S171 (2006) |
Study of DNA in glasslike state by atomic force microscopy: Importance of substrates
Tobenas, S; Bystrenova, E; Radenovic, A; Di Santo, G; Dietler, G
JAPANESE JOURNAL OF APPLIED PHYSICS PART 1-REGULAR PAPERS BRIEF COMMUNICATIONS & REVIEW PAPERS 45, 2345-2348 (2006) |
Numerical simulation of gel electrophoresis of DNA knots in weak and strong electric fields
Weber, C; Stasiak, A; De los Rios, P; Dietler, G
BIOPHYSICAL JOURNAL 90 , 3100-3105 (2006) |
Laser nanotraps and nanotweezers for cold atoms: 3D gradient dipole force trap in the vicinity of scanning near-field optical microscope tip
Klimov, VV; Sekatskii, SK; Dietler, G
OPTICS COMMUNICATIONS 259 , 883-887 (2006) |
Experimental preparation of entangled Bell's vacuum-single exciton and vacuum-biexciton states for pair centers of neodymium ions in a crystal
Sekatskii, SK; Basiev, TT; Basieva, IT; Dietler, G; Fedorov, VV; Karasik, AY; Orlovskii, YV; Pukhov, KK
OPTICS COMMUNICATIONS 259 , 298-303 (2006) |
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| 2005 |
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Direct writing of luminescent nanostructures in lithium fluoride films by X-ray microprobe scanning
Bonfigli, F; Montereali, RM; Marolo, T; Larciprete, R; Gregoratti, L; Danailov, M; Kiskinova, M; Sekatskii, SK; Dietler, G
Advanced Laser Technologies 2004 5850 , 320-327 (2005) |
Scaling exponents and probability distributions of DNA end-to-end distance
Valle, F; Favre, M; De Los Rios, P; Rosa, A; Dietler, G
PHYSICAL REVIEW LETTERS 95 , (2005) |
Superficial and deep changes of cellular mechanical properties following cytoskeleton disassembly
Kasas, S; Wang, X; Hirling, H; Marsault, R; Huni, B; Yersin, A; Regazzi, R; Grenningloh, G; Riederer, B; Forro, L; Dietler, G; Catsicas, S
CELL MOTILITY AND THE CYTOSKELETON 62 , 124-132 (2005) |
Interactions between NEEP21, GRIP1 and GluR2 regulate sorting and recycling of the glutamate receptor subunit GluR2
Steiner, P; Alberi, S; Kulangara, K; Yersin, A; Sarria, JCF; Regulier, E; Kasas, S; Dietler, G; Muller, D; Catsicas, S; Hirling, H
EMBO JOURNAL 24 , 2873-2884 (2005) |
Growth of Pt clusters electrodeposited onto boron-doped diamond films
Riedo, B; Dietler, G; Enea, O
THIN SOLID FILMS 488 , 82-86 (2005) |
Detection of cruciform extrusion in DNA by temperature-gradient gel electrophoresis
Viglasky, V; Danko, P; Adamcik, J; Valle, F; Dietler, G
ANALYTICAL BIOCHEMISTRY 343 , 308-312 (2005) |
Functional dynamics of PDZ binding domains: A normal-mode analysis
De Los Rios, P; Cecconi, F; Pretre, A; Dietler, G; Michielin, O; Piazza, F; Juanico, B
BIOPHYSICAL JOURNAL 89 , 14-21 (2005) |
Gradient of rigidity in the lamellipodia of migrating cells revealed by atomic force microscopy
Laurent, VM; Kasas, S; Yersin, A; Schaffer, TE; Catsicas, S; Dietler, G; Verkhovsky, AB; Meister, JJ
BIOPHYSICAL JOURNAL 89 , 667-675 (2005) |
Interactive measurement and characterization of DNA molecules by analysis of AFM images
Marek, J; Demjenova, E; Tomori, Z; Janacek, J; Zolotova, I; Valle, F; Favre, M; Dietler, G
CYTOMETRY PART A 63A , 87-93 (2005) |
Coherent fluorescence resonance energy transfer in symmetrical clusters of fluorescent centers
Basieva, IT; Sekatskii, SK; Dietler, G
CHEMICAL PHYSICS LETTERS 402 , 433-438 (2005) |
Atomic force microscopy of complex DNA knots
Valle, F; Favre, M; Roca, J; Dietler, G
Physical and Numerical Models in Knot Theory 36 , 161-170 (2005) |
Monte-Carlo simulations of gel-electrophoresis of DNA knots
Weber, C; Fleurant, M; De Los Rios, P; Dietler, G
Physical and Numerical Models in Knot Theory 36 , 149-159 (2005) |
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| 2004 |
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Oscillation
modes of microtubules
Kasas S, Cibert C, Kis
A, et al.
BIOLOGY OF THE CELL 96, 697 (2004) |
Clusters
and superlattices of resonantly interacting
fluorescence centers as quantum computer
hardware
Basieva IT, Sekatskii
SK, Pukhov KK, et al.
LASER PHYSICS 14, 1393 (2004) |
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Mechanical
properties of microtubules explored
using the finite elements method
Kasas S, Kis A, Riederer BM,
et al.
CHEMPHYSCHEM 5, 252 (2004)
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Force
spectroscopy with a small dithering
of AFM tip: A method of direct and continuous
measurement of the spring constant of
single molecules and molecular complexes
Chtcheglova LA, Shubeita GT, Sekatskii
SK, et al.
BIOPHYS J 86, 1177 (2004) |
Folding
of small RNAs displaying the GNC base-pattern:
implications for the self-organization
of the genetic system
Lehmann J, Riedo B, Dietler G
J THEOR BIOL 227, 381 (2004 ) |
Complex
characterization of physiology solution
based magnetic fluid
Timko M, Koneracka M, Kopcansky P, Tomori
Z, Vekas L, Jozefczak A, Skumiel A,
Radenovic A, Dietler G, Bystrenova E,
Lita M
INDIAN J ENG MATER S 11, 276
(2004) |
Active
solubilization and refolding of stable
protein aggregates by cooperative unfolding
action of individual Hsp70 chaperones
Ben-Zvi A, De los Rios P, Dietler
G, Goloubinoff P
J BIOL CHEM 279, 37298 (2004)
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Coherent
fluorescence resonance energy transfer
between two dipoles: full quantum electrodynamics
approach
Klimov V, Sekatskii SK, Dietler G
J MOD OPTIC 51, 1919 (2004) |
Shear
force distance control in a scanning
near-field optical microscope: in resonance
excitation of the fiber probe versus
out of resonance excitation
Lapshin DA, Letokhov VS, Shubeita GT,
Sekatskii SK, Dietler
ULTRAMICROSCOPY 99, 227 (2004)
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| 2003 | TOP |
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Coherent
fluorescence resonance energy transfer:
Construction of nonlocal multiparticle
entangled states and quantum computing
Sekatskii SK, Chergui M, Dietler G
EUROPHYS LETT 63, 21 (2003) |
Low
noise current-to-voltage converter and
vibration damping system for a low-temperature
ultrahigh vacuum scanning tunneling
microscope
L.Libioulle, A.Radenovic, E. Bystrenová
and G.Dietler
Rev. Sc. Instr. 74, 1016 (2003) |
Self
- alignment of a polar molecule colliding
with a solid surface
S. K. Sekatskii
Phys. Rev. A: At. Mol. Opt. Phys. 67,
(2) (2003) |
Scanning
near-field optical microscopy using
semiconductor nanocrystals s a local
fluorescence and fluorescence resonance
energy transfer source
G. T. Shubeita, S. K. Sekatskii, G.
Dietler, I. Potapova, A. Mews and T.
Basché,
J. of Microscopy 210,
274 (2003) |
Near-field
optical microscopy of strongly scattering
microporous metal/polymer membranes
G. T. Shubeita, S. K. Sekatskii, G.
Dietler, S. Takahashi and A. V.Zayats
Opt. Communicat. 217,
23 (2003) |
Anthracycline
dependent heat-induced transition from
positive to negative supercoiled DNA
Viktor Viglasky, Francesco Valle, Jozef
Adamcik, Irene Joab, Dusan Podhradsky
and Giovanni Dietler
Electrophoresis 24,
1703 (2003) |
Interactions
between synaptic vesicle fusion proteins
explored by atomic force microscopy
Yersin A, Hirling H, Steiner P, Magnin
S, Regazzi R, Huni B, Huguenot
P, De Los Rios P, Dietler G, Catsicas
S,Kasas S.
Proc. Natl. Acad. Sci., U S A., PNAS,
100, 8736 (2003) |
Vitrification
of cryoelectron microscopy specimens
revealed by high-speed photographic
imaging
Kasas S, Dumas G, Dietler G, et al.
J MICROSC-OXFORD 211, 48 (2003) |
Large
fluctuations in the disassembly rate
of microtubules revealed by atomic force
microscopy
Thomson NH, Kasas S, Riederer BM, Catsicas
S, Dietler G, Kulik AJ, Forro L
ULTRAMICROSCOPY 97, 239 (2003) |
Fast
processes imaging device
Kasas S, Dumas G, Dietler G
AM J PHYS 71, 493 (2003) |
Characterization
of Atomic Force Microscope Probes at
Low Tempertures
A. Radenovic, E. Bystrenova, L. Libioulle,
F. Valle, G. T. Shubeita, S. Kasas,
G. Dietler
J APPL PHYS 94, 4210 (2003) |
Linking
Functional Genomics and Screening for
new Drugs
A. Yersin, S. Kasas, H. Hirling , S.
Catsicas, G. Dietler, P. De Los Rios,
R. Regazzi
LABORWELT 4, 21 (2003) |
An
application of AFM to measure the spring
constant of single antigen-antibody
complex
L. A. Chtcheglova, G. T. Shubeita, S.
Sekatskii, G. Dietler
Phys. Low-Dim. Str. 3/4, 39 (2003) |
Force
Spectroscopy of Polyclonal and Monoclonal
Anti-Bovine Serum Albumin antibodies
- BSA Complexes
L.A. Chtcheglova and G. Dietler
ACTA PHYSICA POLONICA A 104, 321 (2003) |
AFM
operating at low temperature and under
UHV for biological application
E. Bystrenova A. Radenovic, L. Libioulle
and G. Dietler
NANOTECHNOLOGY submitted |
Study
of probes and substrates for low temperature
AFM and biological applications
A. Radenovic, E. Bystrenova, L. Libioulle
and G. Dietler
ACTA PHYSICA POLONICA 104, 373 (2003) |
Low
noise current-to-voltage converter and
vibration damping system for a low-temperature
ultrahigh vacuum scanning tunneling
microscope
L.Libioulle, A.Radenovic, E. Bystrenová
and G.Dietler
Rev. Sc. Instr. 74, 1016 (2003) |
Self
- alignment of a polar molecule colliding
with a solid surface
S. K. Sekatskii
Phys. Rev. A: At. Mol. Opt. Phys. 67,
(2) (2003) |
Scanning
near-field optical microscopy using
semiconductor nanocrystals s a local
fluorescence and fluorescence resonance
energy transfer source
G. T. Shubeita, S. K. Sekatskii, G.
Dietler, I. Potapova, A. Mews and T.
Basché,
J. of Microscopy 210,
274 (2003) |
Near-field
optical microscopy of strongly scattering
microporous metal/polymer membranes
G. T. Shubeita, S. K. Sekatskii, G.
Dietler, S. Takahashi and A. V.Zayats
Opt. Communicat. 217,
23 (2003) |
Anthracycline
dependent heat-induced transition from
positive to negative supercoiled DNA
Viktor Viglasky, Francesco Valle, Jozef
Adamcik, Irene Joab, Dusan Podhradsky
and Giovanni Dietler
Electrophoresis 24,
1703 (2003) |
Coherent
fluorescence resonance energy transfer:
Construction of nonlocal multiparticle
entangled states and quantum computing
Sekatskii SK, Chergui M, Dietler G
EUROPHYS LETT 63, 21(2003) |
Interactions
between synaptic vesicle fusion proteins
explored by atomic force microscopy
Yersin A, Hirling H, Steiner P, Magnin
S, Regazzi R, Huni B, Huguenot
P, De Los Rios P, Dietler G, Catsicas
S,Kasas S.
Proc. Natl. Acad. Sci., U S A., PNAS,
100, 8736 (2003) |
Vitrification
of cryoelectron microscopy specimens
revealed by high-speed photographic
imaging
Kasas S, Dumas G, Dietler G, et al.
J MICROSC-OXFORD 211, 48 (2003) |
Large
fluctuations in the disassembly rate
of microtubules revealed by atomic force
microscopy
Thomson NH, Kasas S, Riederer BM, Catsicas
S, Dietler G, Kulik AJ, Forro L
ULTRAMICROSCOPY 97, 239 (2003) |
Fast
processes imaging device
Kasas S, Dumas G, Dietler G
AM J PHYS 71, 493 (2003) |
Characterization
of Atomic Force Microscope Probes at
Low Tempertures
A. Radenovic, E. Bystrenova, L. Libioulle,
F. Valle, G. T. Shubeita, S. Kasas,
G. Dietler
J APPL PHYS 94, 4210 (2003) |
Linking
Functional Genomics and Screening for
new Drugs
A. Yersin, S. Kasas, H. Hirling , S.
Catsicas, G. Dietler, P. De Los Rios,
R. Regazzi
LABORWELT 4, 21 (2003) |
An
application of AFM to measure the spring
constant of single antigen-antibody
complex
L. A. Chtcheglova, G. T. Shubeita, S.
Sekatskii, G. Dietler
Phys. Low-Dim. Str. 3/4, 39 (2003) |
Force
Spectroscopy of Polyclonal and Monoclonal
Anti-Bovine Serum Albumin antibodies
- BSA Complexes
L.A. Chtcheglova and G. Dietler
ACTA PHYSICA POLONICA A 104, 321 (2003) |
AFM
operating at low temperature and under
UHV for biological application
E. Bystrenova A. Radenovic, L. Libioulle
and G. Dietler
NANOTECHNOLOGY submitted |
Study
of probes and substrates for low temperature
AFM and biological applications
A. Radenovic, E. Bystrenova, L. Libioulle
and G. Dietler
ACTA PHYSICA POLONICA 104, 373 (2003) |
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| 2002 | TOP |
| |
Amplification
of the Sequences Displaying the Pattern
RNY in the RNA World: The Translation
-> Translation/Replication Hypothesis
J. Lehmann
J. theor. Biol.,
219, 521 (2002) |
Local
fluorescent probes for the fluorescence
resonance energy transfer scanning near-field
optical microscopy
G. T. Shubeita, S. K . Sekatskii, G. Dietler, and
V. S. Letokhov
Appl. Phys. Lett. 80, 2625 (2002) |
Mechanical
properties of high-aspect-ratio atomic-force
microscope tips
G. Janchen,
P. Hoffmann, A. Kriele, H. Lorenz, A.J. Kulik, G.Dietler
APPLIED PHYSICS
LETTERS 80, 4623 (2002) |
Nanomechanics
of microtubules
A. Kis, S. Kasas, B. Babic, A.J. Kulik, W. Benoit, GAD Briggs,
C. Schonenberger, S. Catsicas, L. Forro
PHYSICAL REVIEW LETTERS 89
art. no. 248101 (2002) |
AFM
study of Pt clusters electrochemically
deposited onto boron-doped diamond films
O. Enea, B. Riedo and G. Dietler
NANO LETTERS 2, 241 (2002) |
Simultaneous
trapping and guiding of cold ions and
electrons without externally applied
fields
S.K. Sekatskii and G. Dietler
OPTICS COMMUNICATIONS 210, 251 (2002) |
A
low temperature ultrahigh vacuum atomic
force microscope for biological applications
A.Radenovic, E. Bystrenová , L.Libioulle, M.Taborelli, J.A.Derose and G.Dietler
Rev. Sc. Instr. 74, 1022 (2003) |
Direct
measurement of the absolute value of
the interaction force between the fiber
probe and the sample in a scanning near-field
optical microscope
D.D. Lapshin,
V.S. Letokhov, G.T. Shubeita, S.K. Sekatskii and G. Dietler
APPLIED PHYSICS
LETTERS 81,1503 (2002) |
Effect
of bacteria growth temperature on the
distribution of supercoiled DNA and
its thermal stability
J. Adamcik, V. Viglasky , F. Valle , M. Antalik, D.Podhradsky
and G. Dietler
Electrophoresis 23, 3300 (2002) |
Atomic
force microscopy for imaging and force
mapping of Plasmodium berghei sporozoite
L.Chtcheglova, J. Romero, G. Corradin and G.Dietler
Phys. Low-Dim. Struct.
5/6 189 (2002) |
AFM
structural study of the molecular chaperone
GroEL and its two-dimensional crystals:
an ideal "living" calibration
sample
F. Valle, J.A. DeRose, G. Dietler,
M. Kawe, A. Pluckthun and G. Semenza
ULTRAMICROSCOPY 93, 83 (2002) |
|
| 2001 | TOP |
| |
Imaging
the native structure of the chaperone protein GroEL without fixation using atomic
force microscopy
F. Valle, J.A. DeRose, G. Dietler, M. Kawe, A. Plückthun,
G.Semenza
Journal of Microscopy, 203, 195, (2001) |
On
the possibility of observation of single quadrupoles by Fluorescence Resonance
Energy Transfer Scanning Near-field Optical Microscopy
S. K. Sekatskii,
G. T. Shubeita and G. Dietler
Optics Communications 188, 41 (2001) |
Analysis
of fiber probes of Scanning Near-field Optical Microscope by Field Emission Microscopy
S. K. Sekatskii, B. N. Mironov, D. A. Lapshin, G. Dietler, and V. S. Letokhov
Ultramicroscopy 89, 83 (2001) |
Automatic
classification of HITS into artefacts or solid or gaseous emboli : the matching
pursuit combined with dual-gate TCD
G. Devuyst, G.A. Darbellay, J.-M.
Vesin, M. Ritter, , D.W. Droste, C. Molina, J. Serena, R. Sztajzel, P. Ruchat,
G. Dietler, V. Kemény, D.K. Jung, P.-A. Despland, E.B. Ringelstein, J. Bogousslavsky
STROKE 32, 2803 (2001) |
Combined
evanescent light-electrostatic atom trap of subwavelength size
S. K.
Sekatskii, B. Riedo, G. Dietler
Optics Communications 195, 197 (2001) |
Single
molecule imaging by Atomic Force microscopy of the native chaperonin complex of
the thermophilic archaeon Sulfolobus Solfataricus
F. Valle, G. Dietler,
P. Londei
Biochemical and Biophysical Research Communications 228, 258 (2001) |
Examination
of line crossings by atomic force microscopy
S. Kasas, A. Khanmy-Vital,
G. Dietler
FORENSIC SCIENCE INTERNATIONAL 119, 290 (2001) |
Using
magnetic dipole transitions for fluorescence resonance energy transfer
S. K. Sekatskii and G. Dietler
ANALYTICAL BIOCHEMISTRY 299, 263 (2001) |
Geometrical
and electronic structure of Pd clusters on graphite
M. Bovet, E. Boschung,
J. Hayoz, T. Pillo, G. Dietler, P. Aebi
SURFACE SCIENCE 473, 17 (2001) |
Electron
tunneling time measurement by field-emission microscopy
S.K. Sekatskii
and V.S. Letokhov
PHYSICAL REVIEW B 64, 3311 (2001) |
Localization
of breakage points in knotted strings
P. Pieranski, S.Kasas, G. Dietler,
J. Dubochet and A. Stasiak
NEW JOURNAL OF PHYSICS 3, 101
( 2001) |
The
rupture of knotted strings under tension
G.Dietler and S.Kasas
chapter
in Physical Knots : Knotting, Linking, and Folding Geometrical Objects in R3,
American Mathematical Society. Editors: J.A. Calvo, K.C. Millett ,E.J. Rawdon,
217 (2001). |
|
| 2000 | TOP |
| |
Scanning
near-field optical microscopy based on the heterodyne phase-controlled oscillator
method
G. T. Shubeita, S. K. Sekatskii, B. Riedo, G. Dietler and U. Dürig
J. Appl. Phys. 88, 2921, (2000) |
Towards
the fluorescence resonance energy transfer (FRET) scanning near-field optical
microscopy: investigation of nanolocal FRET processes and FRET probe microscope
S. K. Sekatskii, G. T. Shubeita, M. Chergui, G. Dietler, B. N. Mironov, D.
A. Lapshin and V. S. Letokhov
JETP, 90, 769-777, (2000) |
Time-gated
scanning near-field optical microscopy
S. K. Sekatskii, G. T. Shubeita
and G. Dietler
Appl. Phys. Lett. 77, 2089 (2000) |
Impact
Cratering Study in the Laboratory without a Fast Recording Camera
S. Kasas, G. Dumas, and G. Dietler
Am. J. Phys., 68, 771 (2000) |
Fuzzy
logic algorithm to extract specific interaction forces from atomic force microscopy
data
Sandor Kasas, Beat M. Riederer, Stefan Catsicas, Brunero Cappella,
Giovanni Dietler
Rev. Sci. Intrum. 71, 2082 (2000) |
Examination
of line crossongs by atomic force microscopy
S. Kasas, A. Khanmy-Vital,
G. Dietler
Forensic ScienceInternational, 3011, 1 (2000) |
Setup
for observing living cells using a commercial atomic force microscope
S. Kasas, X. Wang, H. Hirling, S. Catsicas, C. Haeberli, G. Dietler, and Thomson
N.
Rev. Sci. Instrum., 71 4338 (2000) |
Physico-Chemical
constraints connected with the coding properties of the genetic system
J. theor. Biol., 202, 129 (2000) |
Visualization
of single dopant ion's quantum states by field emission microscopy"
Sekatskii SK
SURFACE SCIENCE 453 L303 (2000) |
|
| 1999 | TOP |
| |
Kinetic
of Cellular Viability in Warm versus Cold Ischemia Condition of Kidney Preservation:
A Biometric Study
D. Savioz, J. F. Bolle, J. F. Graf, A. Jeanjacquot,
M. Savioz, G. Dietler, H. Favre, M. Leski, D. Morel, and Ph. Morel
Transplantation, 62, 414 (1996) |
AFM
measurements of the topography and the roughness of ECR plasma treated polypropylene
Coen MC, Dietler G, Kasas S and Groning P
APPLIED SURFACE SCIENCE 103,
27 (1996) |
Direct
observation of one-dimensional diffusion and transcription by Escherichia coli
RNA polymerase
Guthold M, Zhu XS, Rivetti C, Yang GL, Thomson NH, Kasas
S, Hansma HG, Smith B, Hansma PK, Bustamante C
BIOPHYSICAL JOURNAL 77,
2284 (1999) |
Distance
curves by atomic force microscopy
B. Cappella and G. Dietler
Surface Science Reports 34 , 1-104 (1999) |
Investigation
of nanolocal fluorescence resonance energy transfer for scanning probe microscopy
G. T. Shubeita, S. K. Sekatskii, M. Chergui and G. Dietler, V. S. Letokhov
Appl. Phys. Lett. 74, 3453 (1999) |
Near-field
optical excitation as a dipole-dipole energy transfer process
S. Sekatskii
and G. Dietler
Journal of Microscopy, 194, 255 (1999) |
Knotted
fishing line, Covalent bonds, and breaking points (technical comment)
A. Stasiak, A. Dobay, J. Dubochet and G. Dietler
Science 286, 11a (1999) |
Comment
on "Subwavelength diameter of light beams in active media"
S. Sekatskii
and G. Dietler
JEPT Letters, 70, 826-827 (1999) |
| |
| | Invited
Talks | |
| Giovanni
Dietler | |
01.01 |
LA PHYSIQUE DES NOUDS
D'ACTINE ET D'ADN Seminaire
PUMA, UNIL | |
02.01 |
THE PHYSICS OF LINEAR,
CIRCULAR AND KNOTTED DNA Experimentelle
Physik, Uni Ulm, Ulm, Germany | |
03.01 |
LA PHYSIQUE DES NOUDS
Faculté
des Sciences, Université de Rabat, Rabat, Maroc |
| 04.01
| THE
PHYSICS OF KNOTS Department
of Mathematics, University of California, Santa Barbara, USA |
| 04.01
| THE
PHYSICS OF KNOTS J.T.
Watson Laboratory of Applied Physics, California Institute of Technology, Pasadena,
USA | | 04.01
| LOCALIZATION
OF BREAKAGE POINTS IN KNOTTED STRINGS American
Mathematical Society, Spring Meeting, 21-22.4.2001, Las Vegas, USA |
| 05.01
| ASPETTI
FISICI DEL DNA LINEARE, CIRCOLARE E ANNODATO Università
dell'Insubria, Dipartimento di Fisica, Como, Italia |
| 05.01
| DETERMINATION
OF SPECIFIC FORCE INTERACTIONS BY ATOMIC FORCE MICROSCOPY Institut
de Biochimie, Université de Lausanne, Epalinges |
| 07.01
| THE
PHYSICS OF KNOTS Division
of Engineering and Applied Sciences/Department of Physics, Harvard University
, Cambridge , MA 02138 , USA | |
09.01 |
THE PHYSICS OF KNOTS
Structure and
Stability of Biomolecules SSB'01, Kosice, Slovak Republic |
| 01.02
| KNOTS
AND PROTEIN FOLDING:TWO PHYSICAL PROBLEMS FROM BIOLOGY University
of Fribourg , Fribourg, Swizerland | |
01.02 |
LE REPLIEMENT ASSISTÉ
DES PROTÉINES Minisymposium
de Physique Biologique, UNIL, Swizerland |
| 05.02
| IMAGING
BIOLOGICAL SAMPLES BY SCANNING PROBE MICROSCOPY Nestec,
Vers-chez-les-Blancs, Swizerland | |
06.02 |
MOLECULAR MACHINES
Uni Fribourg,
Colloque de Physique, Swizerland | |
06.02 |
LOCAL PROBE MICROSCOPY:
IMAGING BIOLOGICAL MOLECULES Cavtat,
Croatia, Conference « From Solid State to Biophysics » |
| 09.02
| LES
NOUDS FASCINENT AUSSI BIEN LES MATHÉMATICIENS QUE LES BIOLOGISTES ET LES
PHYSICIENS Uni
Lausanne, Séance d'ouverture de l'année académique 02-03,
Faculté des Sciences |
|
Serguei
Sekatski | |
05.01 |
FLUORESCENCE RESONANCE
ENERGY TRANSFER SCANNING NEAR-FIELD OPTICAL MICROSCOPY Seminar in the Centre Nationale
de la Recherche Nuclear, Gif-sur-Yvette, France |
| 05.01
| FLUORESCENCE
RESONANCE ENERGY TRANSFER SCANNING NEAR-FIELD OPTICAL MICROSCOPY Seminar in the
Institute of Optics , University of Aalborg , Denmark |
| 01.02
| FLUORESCENCE
RESONANCE ENERGY TRANSFER SCANNING NEAR-FIELD OPTICAL MICROSCOPY 2 nd United Kingdom
Workshop on the problems of Near-field Optics, London, UK |
| 03.02
| ELECTRON
TUNNELING TIME MEASUREMENT BY FIELD EMISSION MICROSCOPY Seminar in the Institut
de Physique Theoretique, Université de Genève, Swizerland |
| 05.02
| SIMULTANEOUS
TRAPPING OF COLD IONS AND ELECTRONS WITHOUT EXTERNALLY APPLIED FIELDS International
Quantum Electronics Conference, Moscow , Russia |
| 07.02
| ELECTRON
TUNNELING TIME MEASUREMENT BY FIELD EMISSION MICROSCOPY 44 th Int. Field Emission
Symposium, Lyon , France | |
08.02 |
SCANNING NEAR-FIELD
OPTICAL QUANTUM COMPUTER 7 th Int. Conf. on Near-field Optics and Its Applications,
Rochester , USA | |
11.02 |
FLUORESCENCE RESONANCE
ENERGY TRANSFER SCANNING NEAR-FIELD OPTICAL MICROSCOPY Seminar in ENEA, Frascatti,
Italy | | |
| | Ph.D.
Thesis | |
IPMC-LPMV : 13 juin 2008
---------------------------------
Mélanie Favre, Thèse EPFL, no 4101 (2008)
Dir.: Prof. Giovanni Dietler
|
Dr. Melanie Favre has successfully defended her private thesis on 20th May and her public Defense on 13th June 2008
Congratulations for his work and results.
Please Visit WebAlbum
|
|
IPMC - LPMV 4 April 2008
Erika Ercolini, thèse EPFL, no 4041 (2008).
Dir.: Giovanni Dietler
|
  
Dr. Erika Ercolini has successfully defended her private (22 February 2008) and public thesis defense on 4 April 2008
Title : "Scaling properties of DNA knots studied by atomic force microscopy"
Congratulations for his work and results.
Public Defense Webalbum Link |
|
IPMC - LPMV 29 - Feb. 2008
Susana Tobenas, thèse EPFL, no 4035 (2008)
Dir.: Giovanni Dietler
|
Dr. Susana del Carmen Tobenas Borron has successfully defended her private (8 Feb.) and public (29 Feb.) thesis
Title:"Cryo-AFM development for high resolution DNA imaging and spectroscopy"
Congratulations for his work, results and for her new job at Rolex Research
Public Defense Webalbum Link
|
IPMC-LPMV - Dec. 2007
Charles Roduit, thèse EPFL, no 3985 (2007).
Dir.: Sandor Kasas, Stefan Katsikas and Giovanni Dietler's LPMV laboratory
|
 
|
Jeudi 20 décembre 2007 à 17h00, salle CE2
Dr. Charles Roduit , PhD candidate in the EPFL program in Neuroscience, has successfully defended his private and public PhD thesis
"Membrane Elastic Heterogeneity Studied at Nanometrical Scale on Living "
http://library.epfl.ch/en/theses/?nr=3985 |
|
| Lilia
Chtechglova | Quasistatic
and dynamic force spectroscopy of single antigen-antibody complexes and fibrin-fibrinogen
systems
EPFL
- 2004 |
Francesco
Valle | Study
of biomacromolecule conformational change by AFM
UNIL - 2003 |
Aleksandra
Radenovic | Development
of low temperature Atomic Force Microscope for biological application
UNIL
- 2003 | |
George
T. Shubeita | Higer
Resolution Scanning Near-Field Optical Microscoy by Means of Fluorescence Resonance
Energy Transfer
UNIL - 2002 | |
Jean
Lehmann | Propriétés
naturelles de l'ARN et des acides aminés et auto-organisation du système
génétique primitif
UNIL - 2002 | Mélanie
Aeschlimann | Biophysical
models of axonal pathfinding
UNIL - 2000 | |
| | Diploma
Works | |
| Joséphine
Ricou Yanmaz | Etude
des interactions moléculaires dans le complexe récepteur - ligand
avidine-biotine par microscopie à force atomique
EPFL - 2004 |
| Mélanie
Favre | Etude
des propriétés statistiques de l'ADN par AFM
EPFL - 2004 | | Tomas
SAMUELY | Study
of interactions between DNA and proteins by AFM.
UNIL - 2003 | | Thomas
KOHLER | Etude
des interaction entre le fibrinogène et la fibrine activée par l'enzyme
Reptilase au moyen de l'AFM
UNIL - 2003 | | Corinne
KUNZE | Construction
d'un microscope à pinces optiques et piégeage et rotation de différentes
particules
UNIL - 2003 | |
Rui Pedro GONÇALVES |
Détection
in vitro de microemboles circulantes et analyse de la variabilité des caractéristiques
des signaux
UNIL - 2002 | |
Jérôme
KRAYENBUHL | Modélisation
in vitro de l'artère cérébrale moyenne humaine : détection
et analyse des signaux micro-emboliques
UNIL - 2001 |
| Claudio
LUCCHESI | Biomedical
data, algorithms and software : the case of brain emboli identification through
transcranial Doppler ultrasonography
UNIL - 2001 | | Julien
PONARD | Détection
et analyse de signaux micro-emboliques in vitro
UNIL - 2001 |
| Patrick
HUGUENOT | Probing
SNARE protein interactions by atomic force microscopy
UNIL - 2001 | | Céline
CHÈVEAU | Forces
d'interaction entre les domaines de la protéine Ste11p par microscopie
à force atomique
UNIL - 2000 | | Axelle
TAPPONNIER | Etude
de l'ADN par microscopie à force atomique et détermination de l'exposant
critique de Flory
UNIL -1998 |
|
| | Committees
and Honours | |
| ABMI
| ENJEUX-SUISSE
Lundi 1 décembre 2003
La lausannoise Abmi médaillée d’or
par les Américains.
La biotech suisse reçoit de nouveau cette
année le prix de l’innovation technologique du «Wall Street
Journal» | | Claudio
Lucchesi | Start-up
competition de l'IMD 2002-2003 | |
Claudio Lucchesi
| Prix
NETS 2002 d'Entrepreneurship, décerné par la Fondation Gerbert Rüf
| | Claudio
Lucchesi | Prix
Porphyrogénis de HEC Lausanne « pour l'excellence de mon mémoire
de diplôme » dans le cadre du Diplôme Postgrade en Informatique
et Organisation | | Claudio
Lucchesi | prix
« coup de pouce » de la Fondation Liechti |
| |
| TOP | Press
Coverage | |
| | | Flash
n10 septembre 2003
Revue
Polyrama
119 Novembre 2003
- Objectif savoir - Un microscope à
force atomique espionne les neurones par Sylvie Egloff
En première
mondiale, une équipe interdisciplinaire de l’EPFL et de l’UNIL
apporte un éclairage nouveau sur le fonctionnement du cerveau grâce
au microscope à force atomique. L’expérience a été
menée sur les protéines nécessaires à la communication
dans le cerveau. A l’aide de ce microscope, les scientifiques ont pu visualiser,
puis calculer, la force qui agit entre ces protéines clés lors de
l’échange d’information.
L’équipe qui a réalisé
ce travail est dirigée par Stefan Catsicas, professeur en neurobiologie
cellulaire à l’EPFL et compte les biologistes moléculaires
qui ont cloné les protéines étudiées. Alexandre Yersin,
physicien et doctorant en neurobiologie, de même que Sandor Kasas, docteur
en médecine de l’UNIL ont réalisé et supervisé
les expériences avec l’AFM. Le travail s’appuie sur les compétences
du groupe de physique de la matière condensée dirigé par
le professeur Giovanni Dietler à l'EPFL. Afin d’effectuer les
calculs les plus complexes, les chercheurs se sont adjoints l’aide de Paolo
de Los Rios, physicien théoricien, également professeur à
l’UNIL. | Article
Polyrama de novembre 2003
En
première mondiale, une équipe interdisciplinaire de l’EPFL
et de l’UNIL apporte un éclairage nouveau sur le fonctionnement du
cerveau grâce au microscope à force atomique. |
| La
BBC World Service a réalisé avec P. Pieranski et G.Dietler un
interview qui a été diffusé dans leur émission internationale
« Science in Action ». | |
La publication
« Localization of Breaking Points in knotted Strings » avec
P. Pieranski, S. Kasas, G.
Dietler, J. Dubochet, and A. Stasiak dans le New Journal of Physics, 3, 10.1-10.13
(2001) a été l'objet d'un intérêt considérable
dans la presse internationale (Financial Times, Libération, The Guardian,
Corriere della Sera, The Boston Globe, etc). La
revue Science nous a dédié un texte dans leur rubrique Random
Samples (Science, 293 (2001) p. 2) et nous avons été « nommé »
world experts in spaghetti dû a l'utilisation de spaghetti pour faire les
expériences de rupture des nouds. | |
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© 2009 - 2010, EPFL - EPFL SB IPSB - BSP/Cubotron (Bât. sciences physiques UNIL) CH-1015 Lausanne , Switzerland - Tel: +41
021 6930443, Fax: +41 021 6930422
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